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Moving Basic Discoveries to the Clinic and Clinical Findings to the Laboratory

May 22, 2008

The intent of the symposium is to present new and exciting advances in pain research and pain management, featuring work done through NIH support. Topics will include Moving Basic Discoveries to the Clinic and Clinical Findings to the Laboratory. A poster session will include a broad selection of current pain research findings presented by junior investigators. Members of the extramural scientific community, the NIH scientific community, health care providers, and the public are invited to attend. The event will be hosted by the co-Chairs of the NIH Pain Consortium.


Opening Remarks: NIH Pain Consortium co-Chair
Patricia Grady, Ph.D., R.N., FAAN, Director National Institute of Nursing Research


Opening Remarks: American Pain Society Representative
Jennifer Haythornthwaite, Ph.D., Johns Hopkins University


Panel Session: Basic Mechanisms Underlying Pain Therapies
Moderator: John Kusiak, Ph.D., NIDCR

Cannabinoid Analgesia through TRPV1 Desensitization
Ken Hargreaves, D.D.S., Ph.D.

Cannabinoid and Sphingolipid Enhancement of Opioid Antinociception
Sandra Welch, Ph.D.

Migraine and CSD: Effects on the Brain and How We Should Treat It
Maiken Nedergaard, M.D., Ph.D.

Mechanisms of Triptan Action in Migraine and Pain
Andrew Ahn, M.D., Ph.D.

Questions and Answers


Break and Posters in the Atrium


Panel Session: Basic Discoveries: Moving Towards Clinical Care

Selective Targeting of Pain Fibers in Regional Anesthesia
Bruce Bean, Ph.D.

Improgan: A Cannabinomimetic Analgesi
Lindsay Hough, Ph.D.

Intrathecal AAV: A Candidate Platform for Translational Pain Research
Andreas Buetler, M.D.

Matrix Metalloprotease: A New Target for Pain Therapy?
Ji, Ru-Rong, Ph.D.

Questions and Answers


Lunch and Poster Sessions in the Atrium (20 posters from young investigators)


Panel Session: Parallel Pathways: Basic and Clinical Discoveries
Moderator: Kathy Mann-Koepke, Ph.D., NINR

Complex Genetics of Pain Susceptibility
William Maixner, D.D.S., Ph.D.

Genetic Variation in NPY Alters Human Pain/Stress Response and Emotion
David Goldman, M.D.


Break and Posters in the Atrium


Quality of Life and pain in premenopausal women with major depressive disorder: The power study
Ann Berger, M.S.N., M.D.

Behavioral and neural underpinnings of pain processing in major depressive disorder
Irina Strigo, Ph.D.

Questions and Answers


Closing Remarks from NIH Pain Consortium
Linda Porter, Ph.D., Pain Consortium


Panel Discussion: What have we learned from these discoveries?
Moderator, Linda Porter, NINDS Speakers, Poster Presenters, NIH Pain Consortium Members

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