with serious medical illness, fatigue is highly prevalent
and can have a major and adverse effect on quality of life.
There is growing recognition among clinicians of the need
to assess and manage fatigue at all stages of disease. Studies
are needed to clarify the mechanisms that underlie various
types of fatigue, understand the complex epidemiology of the
symptom, and provide an evidence base for management decisions.
To date, little research of this type has been performed.
Fortunately, the past decade has witnessed substantial advances
in fatigue assessment methodologies, and there are now extraordinary
opportunities to advance fatigue-related research and provide
new tools to benefit the quality of life of medically ill