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Delirium Research Sections
Author Bio
Introduction
Currently selected section: Definition And Clinical Features
Patient Population
Consent For Participation
Assessment for Delirium
Clinical Characteristics And Etiology
Management of Delirium
Other Study Implications
Conclusion

Chapter 5: Delirium Research Questions: Definition And Clinical Features
        

Definition of Delirium

Definitions and diagnostic criteria for delirium have evolved over the years as understanding of its pathophysiologic basis has improved. Standardized diagnostic criteria, such as the Diagnostic and Statistical Manual of Psychiatric Disorders 4th edition (DSM-IV) (American Psychiatric Association (APA), 1994) criteria, allow formal confirmation of the diagnosis of delirium for research purposes.

DSM-IV requires the following essential
criteria for a diagnosis of delirium
Disturbance of consciousness (i.e. reduced clarity of awareness of the environment) with reduced ability to focus, sustain, or shift attention.
Change in cognition (e.g. memory deficit, disorientation, language disturbance and perceptual disturbance) that is not better accounted for by a pre-existing, established, or evolving dementia.
Development over a short period of time (usually hours to days) and disturbance tends to fluctuate during the course of the day.
There is evidence from the history, physical examination, or laboratory findings that the disturbance is caused by the direct physiological consequences of a general medical condition.

The DSM-IV classification subdivides delirium by etiology into delirium due to:

  • substance intoxication delirium;
  • substance withdrawal delirium;
  • delirium due to multiple etiologies; and
  • delirium not otherwise specified.
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