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Clinical Research: Constipation Sections
Author Biography
Introduction
What is constipation?
Understanding the problem
Objective Measurement
Subjective Measurement
Currently Selected Section: Measuring Components
Precipitating Factors
Therapeutic Comparisons
Research Questions
Conclusion




Chapter 3: Methods for Clinical Research in Constipation: Measuring Compnents - Slow Transit vs. Evacuation Delay
 

Defecography

Defecography can show both the functional aspects of defecation, and defects in ano-rectal anatomy. The rectum is filled with radio-opaque contrast medium, after which the patient expels the medium under cineradiological screening (Burhenne, 1964). The technique allows the recognition of the importance of the anorectal angle in successful defecation. Normally this angle, formed by the lines of the rectal ampulla and the anal canal, is about 90o and in defecation it increases to around 135o . This increase reflects the relaxation of the puborectalis muscle. Failure of puborectalis to relax, or even a contraction during attempted defecation, is indicated by maintenance or decrease of the anorectal angle, and constitutes a functional outlet obstruction. This has been termed the spastic pelvic floor syndrome, or paradoxical puborectalis contraction (Kuijpers and Strijk, 1984). However, even in normal subjects puborectalis contraction has been described during straining and so this alone is not a clear indication of pathological defecation.

On the other hand, defecography gives an indication of the speed and effectiveness of the act of defecation. It also shows up anatomic variations, such as rectocele, enterocele or intussusception, that may contribute to difficulty in defecation.

Figure 6.1 Megarectum
Graphic depiction of radiograph of severe constipation, described in text
Radiograph of severe constipation, showing loaded colon and megarectum. Courtesy of Dr. John Yiannakou.

Figure 6.2 Rectocele
Graphic depiction of barium enema series, described in text.
Barium enema series in a patient with chronic idiopathic constipation, with evidence of a rectocele. Courtesy of Dr. John Yiannakou.

 

 

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