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Assessing Desirability of Outcome States
Author Biographies
Introduction
Common Health Status Measures
Preference-Based Measures
Direct Utility Elicitation
Issues with Utiliy Assessment
How are Utilities Used?
Currently selected section: Utility and Health Status
Utility and Sociodemographic Factors
Computerized Utility Assessment
Catalogs of Utilities
Case Studies
Conclusions


Chapter 24: Assessing Desirability of Outcome States: Utility and Health Status
        

The relationship between health status and directly elicited utility for current health is complex.

Revicki found that physical function correlated with a categorical rating scale (RS) measure of utility, but not with the standard gamble (SG) (Revicki, 1992). Revicki explained the difference by the introduction of risk with the SG. That is, in order to provide a rating that is meaningful in the VNM utility theory context, the SG requires respondents to consider to what extent they will put life at risk to avoid the health state being rated (Weinstein and Fineberg, 1980), a very different task from the RS.

Current health status is only a partial predictor of current health utility (Llewellyn-Thomas, Sutherland et al., 1991; Tsevat, Goldman et al., 1991). Among survivors of myocardial infarction, the TTO correlated poorly with measures of cardiac functional status (Tsevat, Goldman et al., 1991). Over time, their TTO utilities remained stable and did not correlate with changes in Karnofsky index or measures of cardiac function (Tsevat, Goldman et al., 1993).

In a survey of seriously ill hospitalized patients, Tsevat and co-workers found only weak correlations between current health status and current health utility. There was a weak association between changes in TTO scores over time and changes in ability to perform ADLs (Tsevat, Cook et al., 1995).

Those two studies corroborate many others showing that the relationship between one's current state of health and one's utility for that health state is at best modest (Bombardier, Ware et al., 1986; Churchill, Torrance et al., 1987; Llewellyn-Thomas, Sutherland et al., 1991; Tsevat, Goldman et al., 1991; Llewellyn-Thomas, Thiel et al., 1992; Revicki 1992; Fryback, Dasbach et al., 1993; Tsevat, Goldman et al., 1993; Fowler, Cleary et al., 1995; Nease, Kneeland et al., 1995; Revicki, Wu et al., 1995; Tsevat, Cook et al., 1995; Bosch and Hunink, 1996; Chen, Daley et al., 1996; Nease, Tsai et al., 1996; Nichol, Llewellyn-Thomas et al., 1996; Stigglebout, de Haes et al., 1996; Tsevat, Solzan et al., 1996; Perez, McGee et al., 1997; Bartman, Rosen et al., 1998; Bult, Hunink et al., 1998; Patrick, Mathias et al., 1998)

There is no a priori reason that health utilities should correlate strongly with health status. Many individuals with health problems prefer to live as long as possible, even with the health problems, rather than trade time for perfect health, as health may not be the only thing that matters to everyone (Tsevat, 2000).

Utility for current health is multifactorial. It is affected by, but not well predicted by, each of several factors, including major diagnosis, number of chronic conditions, affective state, and functional status. Previous studies that have examined the correlation of physical function with utility for current health have relied on summary scores of physical function and thus have not provided a mapping of specific states of ADL impairment to utility for life with those impairments. Methods developed by Goldstein and colleagues, as described below, address these problems by using the theoretically preferred SG rather than the TTO, and by providing detailed descriptions of ADL dependency to allow for mapping to utility.

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