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Assessing Desirability of Outcome States
Author Biographies
Introduction
Common Health Status Measures
Preference-Based Measures
Currently selected section: Direct Utility Elicitation
Issues with Utiliy Assessment
How are Utilities Used?
Utility and Health Status
Utility and Sociodemographic Factors
Computerized Utility Assessment
Catalogs of Utilities
Case Studies
Conclusions


Chapter 24: Assessing Desirability of Outcome States: Direct Utility Elicitation
         

In utility elicitation with SG, the respondent is asked to compare a known, intermediate state to a gamble, and to choose which of the two is preferable.

The gamble has one of two outcomes:

  • The best health state under consideration (often "perfect health"), with probability p, or
  • The worst health state under consideration (often "dead"), with probability 1-p.

In decision models, these outcomes can be described as any outcomes suitable to the question. In health utility assessments, these outcomes are conventionally set as perfect health versus immediate and painless death.

The probability in the gamble is varied until the decision maker is indifferent between the gamble and the intermediate health state: the probability at which the decision-maker is indifferent is the utility of the health state (Sox, Blatt et al., 1988). For example, if the subject is willing to take up to a 20% risk of death in exchange for an 80% chance of perfect health rather than accept the intermediate state for certain, then the utility of the intermediate state is 80% or 0.8.

The figure below illustrates the standard reference gamble for assessing the utility for a lifetime of back pain. The left side of the figure shows the "sure thing" - lifetime of back pain - for which the utility is to be determined. The right side shows the gamble involved in undergoing a risky procedure with a risk of perioperative death. The probability, shown as p in the figure, is varied until the respondent is indifferent between the "sure thing" and the risky procedure.

Figure 7-5 Standard Reference Gamble for Assessment of the Utility for a Lifetime of Back Pain
Graphic depiction of standard reference gamble, described in text

 

The SG is the rating method best grounded in VNM expected utility theory. However, the SG can be difficult to understand, because it requires mental comparison of a probabilistic outcome with a certain outcome.

The TTO is a direct question about how much life expectancy an individual would trade off to improve quality of life. It attempts to present the respondent with a task that some believe is simpler than the SG task, while preserving an element of trade-off in the assessment (Torrance, 1982). The TTO utility equals one minus the maximum proportion of time that the subject is willing to trade off. For example, if she is willing to give up up to 1/10th of her life expectancy in return for perfect health, her utility for the intermediate health state is 1-0.1, or 0.9.


Health State Classification Systems

Three common health state classification systems are characterized in the table below. Similarities and difference in these methods are detailed in the discussion that follows.

Table 1 Health State Classification Systems
Health Classification System
Consists of
Quality of Well-Being Scale (QWB)
  • 3 Scales of function
  • symptoms and problems
Health Utilities Index (HUI)
  • 8 attributes
  • 5-6 levels per attribute
EQ-5D
  • 5 attributes
  • 3 levels per attribute

Additional information about these systems is available at the following website: http://www.medicine.ucsd.edu/fpm/hoap/instruments.html.

Relationship of Health Status and Utility
The relationship between health status and utilities derived from health state classification systems is by definition strong: Utilities are assigned based on the health state.

In contrast, numerous studies have demonstrated that the correlation between one's current state of health and one's TTO or SG utility for that health state is at best modest (Tsevat, 2000). For example, for two people who are blind, one may consider blindness to be a severe problem associated with a low utility, while the other may consider that blindness is not such a severe problem, with a higher utility.

For individual decision-making, since health status does not correlate well with utility, a health state classification system may not be optimal, and it may be preferable to use directly assessed utilities.

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