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Clinical Trials in TMD Sections
Author Bio
Introduction
The Biopsychosocial Model
Designing Multicenter RCTs
Players in an RCT
Currently selected section: Randomization
Trial Design Quality
TMD Case Definition
Endpoints and Outcome Measures
Blinding & Masking
Study Sample Size
Number and Nature of Interventions
Study Length and Follow up
Intent-to-treat Analyses and Sample Size
Compliance
Multicenter RCTs
Implementing RCTs: Practical Issues
Analysis of TMD Trials
Conclusions
Acknowledgments
Appendix A
Appendix B

 

Chapter 22: Clinical Trials in Temporomandibular: Randomization
          

Question 5.1

The table below shows self-reported pain levels for TMD patients recruited into an RCT that required a pain level of at least 5.0 (on a 10-point VAS scale) for entry. With the mean pain level for the 10 patients at 6.8, how many patients might have lower pain levels on repeated measurement, by chance alone (i.e., regression to the mean)?

Subject # Pain Level
(0 -10 VAS)
1
5.0
2
9.2
3
6.0
4
5.5
5
8.3
6
7.5
7
6.5
8
5.0
9
8.7
10
6.0

Selection A10 patients
Selection B5 patients
Selection C3 patients
Selection D2 patients

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