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A randomized control
trial (RCT) is a scientific experiment widely acknowledged as
the most valid study design to evaluate the effect of treatment
on human diseases and conditions. Temporomandibular disorders
(TMD) are a common, but puzzling, chronic orofacial pain problem
that confronts dentistry. While TMD has been a subject of research
for decades, much of existing data lack quality due to methodological
problems in the design of the studies.
This chapter discusses
the principles and methods for conducting randomized controlled
trials (RCTs) that investigate the treatment and management of
temporomandibular disorders (TMD). It includes discussion of:
- Available evidence
and models for TMD
- Design features
and practical considerations when designing a TMD RCT
- Practical matters
when conducting a TMD RCT
- Issues to consider
when analyzing data from a TMD RCT
Prior to exploring
the chapter, some users may find it helpful to review some or
all of the background resources below:
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