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Human Experimental Pain Models
Author Bios
Learning Objectives
Clinical Significance and Phenomenology
Complex Diseases: Need to Simplify
Model Requirements
Brief and Sustained Experimental Pain
Choice of the Pain Stimulus
A Model Design for Pain Experimentation
Experiential Adjustment
Choice of Stimulation Site
Stimulation Site for a Study of TMJD
Experimental Design
Model Validation: Level 1
Model Validation: Level 2
Model Validation: Level 3
Model Validation: An Example
Cross-Validation with Other Model Systems
Model Systems as Tools
Sample Size Estimation
Potential Difficulties
Currently selected section: Conclusion

 

Chapter 21: Human Experimental Pain Models: Conclusion
        

Question 20.1: Answer

By applying a brief standardized stimulus, injected into the target tissue, low and high pain responders are easily identified. For a given stimulus magnitude, high pain responders report greater pain intensity than low pain responders as illustrated below.

 

Figure 20.1 Pain Response and Intensity
Graphic depiction of pain response and intensity, described in text.

 

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