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Chapter 21: Human Experimental Pain Models by Christian S. Stohler, DDS, Dr. Med. Dent. University of Maryland, Baltimore College of Dental Surgery, Dental School Baltimore, MD, U.S.A
         
Author Biography
Learning Objectives
Clinical Significance and Phenomenology

Complex Diseases: Need to Simplify

Model Requirements
Brief and Sustained Experimental Pain
Choice of the Pain Stimulus
A Model Design for Pain Experimentation
Experiential Adjustment of Stimulus Intensity
Choice of Stimulation Site
Choice of Stimulation Site for a Study of TMJD
Experimental Design
Model Validation: Level 1
Model Validation: Level 2
Model Validation: Level 3
Model Validation - An Example
Cross-Validation with Other Model Systems
Model Systems as Tools in Symptom Research
Sample Size Estimation
Potential Difficulties
Conclusion
 Figures Tables Question
Figure 2.1
Figure 7.1
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Figure 15.1
Figure 19.1
Figure 20.1
Figure 20.2
Table 4.1
Table 4.2
Table 5.1
Table 6.1
Table 12.1
Table 15.1
Table 16.1
Table 17.1
Question 6.1
Question 6.2
Question 10.1
Question 10.2
Question 10.3
Question 10.4
Question 10.5
Question 20.1
Question 20.2