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Problem
6.3
An investigator is carrying
out a single-dose postoperative assessment to learn the
relative potency of a new opioid-like analgesic, Drug R,
to morphine. Because of financial constraints, he only tests
one dose of each drug—Drug R, 10 mg, and morphine, 7.5 mg,
in groups of 50 patients each and gets the following results
for analgesia (below, left panel) and for sedation (right
panel), the most important clinical side effect of Drug
R.
Assume that the standard errors
[not shown] were quite small compared to the differences
in effects.
Question
6.3.1
What can one say about the
comparison of the likely usefulness of Drug R and morphine
from the above two graphs?
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