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A Study of Insomnia and Sleep Loss
Author Bio
Part I
Part II
Using a Stress Framework
Protocol Design
Currently selected section: SNS Activation
Sleep Misperception and Loss
Insomnia and Performance Testing
Insomnia and Emotional Arousal
Yoked Control Design
Effects of Sleep Loss
Insomnia and Somatic Symptoms
Conclusion
 
 
 
 


Chapter 15: Challenges to the Study of Insomnia and Sleep Loss: Measurement and Evaluation of SNS Activation
        

The power within each band is calculated as the area under the respective frequency portion of the power spectrum density curve. The high frequency power band is considered to reflect PSNS activity as mediated through the vagus nerve. Such a rhythm is generated through intrathoracic pressure changes and mechanical variations associated with breathing and is therefore synchronous with the respiratory rate. Although sources contributing to the relative power in the low frequency range are controversial, it is believed to be a function of mixed PSNS and SNS activity. An increase in low frequency power has consistently been observed as a consequence of sympathetic activation. A ratio of the power in the low to high bands often is used to infer SNS activity (Akselrod, 1995). A variety of control and noise sources affect ANS-driven heart rate fluctuations, making data selection and analysis tricky and controversial, but standardization of data collection, scoring algorithms and interpretation of the data are increasingly becoming accepted.

In a study of heart period and heart rate variability analysis by group and sleep stage with psychophysiological-type insomnia subjects matched to control subjects, the following data were graphed (Bonnet and Arand, 1998)

Figure 3.3.6: Heart Beat-to-Beat (BB) Intervals in People With and Without Psychophysiological-type Insomnia by Sleep Stage
Graphic depiction of interval between heartbeats and sleep stage, described in text.

Source: Bonnet MH, Arand DL. Heart rate variability in insomniacs and normal sleepers. Psychosomatic Medicine. 1998; 60:610-615. Reprinted with permission from Lippincott Williams and Wilkinson. http://www.lww.com.

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Figure 3.3.7: Ratio of Low-to-High Frequency Spectral Power in People With and Without Psychophysiological-type Insomnia by Sleep Stage
Graphic depiction of ratio of low to high frequency spectral power and sleep stage, described in text.

Source: Bonnet MH, Arand DL. Heart rate variability in insomniacs and normal sleepers. Psychosomatic Medicine. 1998; 60:610-615. Reprinted with permission from Lippincott Williams and Wilkinson. http://www.lww.com.

Question 3.3.1

The data from the studies just reviewed (Figures 3.3.1, 3.3.2, 3.3.3, 3.3.6, and 3.3.7) show conflicting results, with heart rate tending to be both faster and slower in people with insomnia as compared to those without insomnia.
Selection A
True
Selection B
False

Question 3.3.2

There tends to be a greater dominance of SNS activity in people with psychophysiological-type insomnia as compared to those people without insomnia.
Selection A
True
Selection B
False

Question 3.3.3

The data from these three studies corroborate the postulate that stress hyperactivation is a feature of insomnia, at least in insomnia of the psychophysiological-type.
Selection A
True
Selection B
False

 

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