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Chemotherapy-Related Nausea & Vomiting
Author Bio
Introduction
What Causes Nausea & Vomiting?
Automatic Nervous System
Chemotherapy Induced NV
NV Control
Issues in Research Design
Currently selected section: Case Study 1
Case Study 2
Summary


Chapter 11: Chemotherapy-Related Nausea & Vomiting: Case Study 1
         In the case study presented below, the challenge is to design an experiment examining the efficacy of the component parts of a behavioral intervention for the treatment of anticipatory nausea. [Note: An experiment designed to answer this research question was conducted in the early 1980's (Morrow, 1986) by the author of this chapter and is described below.]

Background

Several groups of researchers reported that anticipatory nausea was a widespread problem, was most likely a learned or conditioned response to treatment, and that the symptoms were refractory to standard antiemetic therapy (Burish et al., 1981; Morrow, 1982; Redd et al., 1982).

A previous experiment identified a potential treatment and key characteristic that would encourage its use (Morrow et al., 1982).

  • The behavioral treatment of systematic desensitization (SD) was found to be significantly more effective in controlling anticipatory side effects resulting from chemotherapy than a counseling intervention or no treatment.
  • The less professional time required for a behavioral intervention, the more applicable that intervention is for widespread clinical use in busy cancer treatment settings.

 

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