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Chemotherapy-Related Nausea & Vomiting
Author Bio
Introduction
What Causes Nausea & Vomiting?
Automatic Nervous System
Chemotherapy Induced NV
NV Control
Currently selected section: Issues in Research Design
Case Study 1
Case Study 2
Summary


Chapter 11: Chemotherapy-Related Nausea & Vomiting: Issues in Research Design
        

Accrual

Relatively few patients with cancer are enrolled in clinical trials. Only about 25,000 (2.5%) of approximately 1 million patients newly diagnosed with cancer each year in the United States are enrolled in clinical trial protocols, despite estimates that 12-44% of patients with cancer are eligible for entry into protocols (Gotay, 1991).

Accrual figures are somewhat higher (10% to 30 %) in clinics associated with the National Cancer Institute-sponsored Community Clinical Oncology Program (CCOP), which was formed for the purpose of expanding the population of both physicians and patients available for participation in clinical trials (American Medical Association Council on Scientific Affairs, 1991).

Question 6.1


What do you think is the most commonly cited reason for eligible patients not being enrolled in available protocols?

Selection APatient's fears of being a "guinea pig"
Selection BProblems with medical insurance coverage
Selection CPhysician-related factors
Selection DNone of the above


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